Effect of Crocidolite Fibers on the Cathepsin B-like Enzyme Activity in HL-60 Cells.

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[Effect of crocidolite fibers on the cathepsin B-like enzyme activity in HL-60 cells].

In a previous study, we found that crocidolite (an asbestos fiber) had an inhibitory effect on the differentiation process of HL-60 cells induced by dimethyl sulfoxide (DMSO). Here we describe the cathepsin B-like enzyme HL-60 cells and the changes of its activity during cell differentiation with or without crocidolite treatment. The cathepsin B-like enzyme in HL-60 cell extracts had almost the...

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ژورنال

عنوان ژورنال: Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)

سال: 1992

ISSN: 0021-5082,1882-6482

DOI: 10.1265/jjh.46.1104